Ednrb^tm1.1Nat
Targeted Allele Detail

Summary

• Symbol: Ednrb^tm1.1Nat
• Name: endothelin receptor type B; targeted mutation 1.1, Jeremy Nathans
• MGI ID: MGI:4438377
• Gene: Ednrb Location: Chr14:104052055-104081764 bp, - strand Genetic Position: Chr14, 53.05 cM
• Alliance: Ednrb^tm1.1Nat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158267
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A LoxP site was inserted upstream of the start codon within the second exon of the targeted gene. A second LoxP site was placed downstream of the second exon, within the second intron. Adjacent to the second LoxP site is an Frt site left over after the excision of the PGK-neo selectable marker. (J:158267)

Generation of the Ednrb^tm1.1Nat and Ednrb^tm1.2Nat alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ednrb Mutation: 104 strains or lines available

References

• Original: J:158267 Nathans J, Direct Submission for Ednrb^tm1Nat. MGI Direct Data Submission 2009. 2010
• All: 7 reference(s)