Tg(Thy1-TARDBP)4Singh
Transgene Detail

Summary

• Symbol: Tg(Thy1-TARDBP)4Singh
• Name: transgene insertion 4, Samir Kumar-Singh
• MGI ID: MGI:4438490
• Synonyms: TAR4
• Transgene: Tg(Thy1-TARDBP)4Singh Location: unknown
• Alliance: Tg(Thy1-TARDBP)4Singh page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Thy1-TARDBP)4Singh expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TARDBP (23435)

  Tardbp

  (MGI:2387629)

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:157550 Wils H, et al., TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3858-63
• All: 11 reference(s)