Slc20a1^tm1.1Lbek
Targeted Allele Detail

Summary

• Symbol: Slc20a1^tm1.1Lbek
• Name: solute carrier family 20, member 1; targeted mutation 1.1, Laurent Beck
• MGI ID: MGI:4438613
• Synonyms: PiT1^lox
• Gene: Slc20a1 Location: Chr2:129040684-129053536 bp, + strand Genetic Position: Chr2, 62.79 cM
• Alliance: Slc20a1^tm1.1Lbek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157997
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: An frt flanked neo cassette was inserted in intron 5, and exon 5 was flanked 5' and 3' with loxP sites 532 bp upstream and 934 bp downstream. The selection cassette was removed by flp mediated recombination. The amount of wild-type RNA is unchanged. (J:157997)

Generation of the Slc20a1^tm1Lbek, Slc20a1^tm1.1Lbek and Slc20a1^tm1.2Lbek alleles

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc20a1 Mutation: 36 strains or lines available

References

• Original: J:157997 Beck L, et al., The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development. PLoS One. 2010;5(2):e9148
• All: 6 reference(s)