Dnm1l^tm1.2Miha
Targeted Allele Detail

Summary

• Symbol: Dnm1l^tm1.2Miha
• Name: dynamin 1-like; targeted mutation 1.2, Katsuyoshi Mihara
• MGI ID: MGI:4438631
• Synonyms: Drp1^-
• Gene: Dnm1l Location: Chr16:16130094-16176823 bp, - strand Genetic Position: Chr16, 10.12 cM
• Alliance: Dnm1l^tm1.2Miha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158142
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was removed by cre mediated recombination. (J:158142)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnm1l Mutation: 44 strains or lines available

References

• Original: J:158142 Ishihara N, et al., Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol. 2009 Aug;11(8):958-66
• All: 4 reference(s)