Cd84^tm1Pls
Targeted Allele Detail

Summary

• Symbol: Cd84^tm1Pls
• Name: CD84 antigen; targeted mutation 1, Pamela L Schwartzberg
• MGI ID: MGI:4438772
• Gene: Cd84 Location: Chr1:171667265-171718285 bp, + strand Genetic Position: Chr1, 79.54 cM
• Alliance: Cd84^tm1Pls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157915
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The second exon was replaced by two stops codons and a neo cassette by homologous recombination. Lack of expression was verified by flow cytometry. (J:157915)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd84 Mutation: 54 strains or lines available

Notes

ES cell line = HGTC-8.

References

• Original: J:157915 Cannons JL, et al., Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 2010 Feb 26;32(2):253-65
• All: 6 reference(s)