Nr2f1^tm2.1Mjts
Targeted Allele Detail

Summary

• Symbol: Nr2f1^tm2.1Mjts
• Name: nuclear receptor subfamily 2, group F, member 1; targeted mutation 2.1, Ming-Jer Tsai
• MGI ID: MGI:4439069
• Synonyms: COUP-TFI^f
• Gene: Nr2f1 Location: Chr13:78337090-78346954 bp, - strand Genetic Position: Chr13, 41.38 cM
• Alliance: Nr2f1^tm2.1Mjts page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157924
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into exon 1 upstream of the start site and an frt flanked neo cassette and second loxP cassette were inserted into intron 1. Flp mediated recombination removed the neo cassette. (J:157924)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nr2f1 Mutation: 25 strains or lines available

References

• Original: J:157924 Tang K, et al., COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development. 2010 Mar;137(5):725-34
• All: 2 reference(s)