Lrrc3b^tm1.1Reed
Targeted Allele Detail

Summary

• Symbol: Lrrc3b^tm1.1Reed
• Name: leucine rich repeat containing 3B; targeted mutation 1.1, Randall R Reed
• MGI ID: MGI:4439362
• Synonyms: Lrrc3b^deltaYFP, Lrrc3b::tauYFP
• Gene: Lrrc3b Location: Chr14:7030776-7112248 bp, + strand Genetic Position: Chr14, 7.08 cM
• Alliance: Lrrc3b^tm1.1Reed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158375
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A tauYFP reporter and floxed neo cassette replaced the initiation codon and entire coding region. The absence of protein expression was confirmed by western blot analysis on olfactory epithelium extracts. YFP expression mimics endogenous expression in mature olfactory neurons from P10, P20, and adult mice. (J:158375)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrc3b Mutation: 20 strains or lines available

References

• Original: J:158375 Bennett MK, et al., Odor-evoked gene regulation and visualization in olfactory receptor neurons. Mol Cell Neurosci. 2010 Apr;43(4):353-62
• All: 1 reference(s)