Snap23^tm1.1Paro
Targeted Allele Detail

Summary

• Symbol: Snap23^tm1.1Paro
• Name: synaptosomal-associated protein 23; targeted mutation 1.1, Paul A Roche
• MGI ID: MGI:4439388
• Synonyms: Snap23^delta
• Gene: Snap23 Location: Chr2:120398152-120431736 bp, + strand Genetic Position: Chr2, 60.37 cM, cytoband E5
• Alliance: Snap23^tm1.1Paro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158506
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 2 was removed by cre mediated recombination. Reduced protein expression was confirmed by western blot analysis on extracts from heterozygous mice. (J:158506, J:171444)

Generation of the Snap23^tm1Paro, Snap23^tm1.1Paro, and Snap23^tm1.2Paro alleles

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snap23 Mutation: 31 strains or lines available

References

• Original: J:158506 Suh YH, et al., A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat Neurosci. 2010 Mar;13(3):338-43
• All: 3 reference(s)