Dag1^tm3Kcam
Targeted Allele Detail

Summary

• Symbol: Dag1^tm3Kcam
• Name: dystroglycan 1; targeted mutation 3, Kevin P Campbell
• MGI ID: MGI:4440458
• Synonyms: DG^betacyt
• Gene: Dag1 Location: Chr9:108082060-108141176 bp, - strand Genetic Position: Chr9, 59.08 cM
• Alliance: Dag1^tm3Kcam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158199
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A loxP flanked Neo was inserted within intron 1 and exon 2 was truncated, removing the cytoplasmic domain, by the insertion of stop codons in all three reading frames by homologous recombination. (J:158199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dag1 Mutation: 109 strains or lines available

References

• Original: J:158199 Satz JS, et al., Visual impairment in the absence of dystroglycan. J Neurosci. 2009 Oct 21;29(42):13136-46
• All: 3 reference(s)