Tbc1d32^bromi
Chemically induced Allele Detail

Summary

• Symbol: Tbc1d32^bromi
• Name: TBC1 domain family, member 32; bromi
• MGI ID: MGI:4440463
• Gene: Tbc1d32 Location: Chr10:55890389-56104785 bp, - strand Genetic Position: Chr10, 28.45 cM
• Alliance: Tbc1d32^bromi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a A to G transition in the intron 10 exon 11 splice acceptor site. Absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:101649, J:158583)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	65 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbc1d32 Mutation: 58 strains or lines available

References

• Original: J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
• All: 4 reference(s)