Hdac2^tm1.2Pmt
Targeted Allele Detail

Summary

• Symbol: Hdac2^tm1.2Pmt
• Name: histone deacetylase 2; targeted mutation 1.2, Patrick Matthias
• MGI ID: MGI:4440562
• Gene: Hdac2 Location: Chr10:36850540-36877885 bp, + strand Genetic Position: Chr10, 19.44 cM, cytoband B1
• Alliance: Hdac2^tm1.2Pmt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157903
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 6 was floxed and a neo cassette with a 3' loxP site was inserted within intron 7.The selection cassette and exon 6 were removed by cre mediated recombination. (J:157903)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdac2 Mutation: 40 strains or lines available

References

• Original: J:157903 Yamaguchi T, et al., Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev. 2010 Mar 1;24(5):455-69
• All: 1 reference(s)