Tg(SFTPC-cre)#Mliu
Transgene Detail

Summary

• Symbol: Tg(SFTPC-cre)#Mliu
• Name: transgene insertion, Mingyao Liu
• MGI ID: MGI:4440739
• Synonyms: SPC-Cre
• Transgene: Tg(SFTPC-cre)#Mliu Location: unknown
• Alliance: Tg(SFTPC-cre)#Mliu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(SFTPC-cre)#Mliu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  SFTPC (6440)

  Sftpc

  (MGI:109517)

• Mutation details: The cDNA encoding cre recombinase and a nuclear localization signal (NLS) was cloned downstream of the human 3.7 kb SFTPC promoter sequence to generate the transgene construct. Transgenic founders were bred to Z/EG reporter mice to verify cre activity. One founder line was analyzed further and was designated # (no line number was specified in the reference). (J:158566)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	SFTPC (human) Summary of all recombinase alleles driven by SFTPC. Alliance human SFTPC gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:158566 Mura M, et al., Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability. Am J Pathol. 2010 Apr;176(4):1725-34
• All: 1 reference(s)