Alas1^tm1.1Mym
Targeted Allele Detail

Summary

• Symbol: Alas1^tm1.1Mym
• Name: aminolevulinic acid synthase 1; targeted mutation 1.1, Masayuki Yamamoto
• MGI ID: MGI:4440831
• Synonyms: Alas1^GFP
• Gene: Alas1 Location: Chr9:106110654-106125153 bp, - strand Genetic Position: Chr9, 57.46 cM, cytoband F1
• Alliance: Alas1^tm1.1Mym page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158435
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A EGFP and floxed neo caseette were inserted upstream of exon 2. Cre mediated recombination removed the neo cassette. Transcript levels in the liver and testis are unaffected in heterozygous mice. (J:158435)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alas1 Mutation: 48 strains or lines available

References

• Original: J:158435 Okano S, et al., Indispensable function for embryogenesis, expression and regulation of the nonspecific form of the 5-aminolevulinate synthase gene in mouse. Genes Cells. 2010 Jan;15(1):77-89
• All: 2 reference(s)