Runx1^tm1.1Stkd
Targeted Allele Detail

Summary

• Symbol: Runx1^tm1.1Stkd
• Name: runt related transcription factor 1; targeted mutation 1.1, Shu Takeda
• MGI ID: MGI:4440931
• Synonyms: Runx1^f
• Gene: Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
• Alliance: Runx1^tm1.1Stkd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158761
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette was inserted downstream of exon 4. Cre-mediated recombination removed the neo cassette leaving exon 4 floxed. (J:158761)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx1 Mutation: 34 strains or lines available

References

• Original: J:158761 Kimura A, et al., Runx1 and Runx2 cooperate during sternal morphogenesis. Development. 2010 Apr;137(7):1159-67
• All: 2 reference(s)