Ddx11^tm1Jiml
Targeted Allele Detail

Summary

• Symbol: Ddx11^tm1Jiml
• Name: DEAD/H box helicase 11; targeted mutation 1, Jill M Lahti
• MGI ID: MGI:4441046
• Gene: Ddx11 Location: Chr17:66430515-66459169 bp, + strand Genetic Position: Chr17, 35.26 cM
• Alliance: Ddx11^tm1Jiml page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158490
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3 through 5 were deleted through homologous recombination. (J:158490)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx11 Mutation: 46 strains or lines available

References

• Original: J:158490 Inoue A, et al., Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation. Cell Cycle. 2007 Jul 1;6(13):1646-54
• All: 3 reference(s)