Ccl17^tm1.1Ifo
Targeted Allele Detail

Summary

• Symbol: Ccl17^tm1.1Ifo
• Name: C-C motif chemokine ligand 17; targeted mutation 1.1, Irmgard Foerster
• MGI ID: MGI:4441162
• Synonyms: CCL17^E, CCL17/EGFP
• Gene: Ccl17 Location: Chr8:95537081-95538664 bp, + strand Genetic Position: Chr8, 46.85 cM
• Alliance: Ccl17^tm1.1Ifo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159098
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: EGFP, polyadenylation sequence, and an frt flanked neo cassette were inserted into exon 2. Flp mediated recombination removed the neo cassette. The absence of protein expression was confirmed by ELISA on bone marrow-derived dendritic cells. (J:159098)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccl17 Mutation: 11 strains or lines available

References

• Original: J:159098 Alferink J, et al., Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med. 2003 Mar 3;197(5):585-99
• All: 22 reference(s)