Clec5a^tm1Cua
Targeted Allele Detail

Summary

• Symbol: Clec5a^tm1Cua
• Name: C-type lectin domain family 5, member a; targeted mutation 1, Daniel J Cua
• MGI ID: MGI:4441169
• Synonyms: Mdl1^-, MDL-1^-
• Gene: Clec5a Location: Chr6:40551832-40562739 bp, - strand Genetic Position: Chr6, 18.82 cM, cytoband B2
• Alliance: Clec5a^tm1Cua page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158811
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exons 1 through 6 were replaced with a flanked neo cassette. (J:158811)

Generation of the Clec5a^tm1Cua allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec5a Mutation: 19 strains or lines available

References

• Original: J:158811 Joyce-Shaikh B, et al., Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J Exp Med. 2010 Mar 15;207(3):579-89
• All: 6 reference(s)