Adam22^tm1.1Mejr
Targeted Allele Detail

Summary

• Symbol: Adam22^tm1.1Mejr
• Name: a disintegrin and metallopeptidase domain 22; targeted mutation 1.1, Dies Meijer
• MGI ID: MGI:4441313
• Synonyms: Adam22^Lox
• Gene: Adam22 Location: Chr5:8122352-8418160 bp, - strand Genetic Position: Chr5, 3.39 cM
• Alliance: Adam22^tm1.1Mejr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158973
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:158973)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adam22 Mutation: 72 strains or lines available

References

• Original: J:158973 Ozkaynak E, et al., Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling. J Neurosci. 2010 Mar 10;30(10):3857-64
• All: 4 reference(s)