Sirt7^tm1Fwa
Targeted Allele Detail

Summary

• Symbol: Sirt7^tm1Fwa
• Name: sirtuin 7; targeted mutation 1, Frederick W Alt
• MGI ID: MGI:4441347
• Synonyms: VG321
• Gene: Sirt7 Location: Chr11:120509197-120515840 bp, - strand Genetic Position: Chr11, 84.34 cM
• Alliance: Sirt7^tm1Fwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177027
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Not Specified
• Mutation details: A targeting vector was designed to replace exons 4-11 by placing a beta-galactosidase (lacZ) cassette in the 5' end of exon 4. (J:177027)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sirt7 Mutation: 20 strains or lines available

References

• Original: J:177027 Alt FW, Direct Data Submission. MGI Direct Data Submission. 2011
• All: 11 reference(s)