Intu^tm1.2Aliu
Targeted Allele Detail

Summary

• Symbol: Intu^tm1.2Aliu
• Name: inturned planar cell polarity protein; targeted mutation 1.2, Aimin Liu
• MGI ID: MGI:4441401
• Synonyms: Intu^deltaEx2
• Gene: Intu Location: Chr3:40585559-40659206 bp, + strand Genetic Position: Chr3, 19.46 cM
• Alliance: Intu^tm1.2Aliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159120
• Parent Cell Line: BK4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed exon 2. The absence of protein expression was confirmed by western blot analysis on E10.5 embryo extracts. (J:159120)

Expression

In Mice Carrying this Mutation:	84 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Intu Mutation: 45 strains or lines available

References

• Original: J:159120 Zeng H, et al., PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals. Dev Biol. 2010 Mar 15;339(2):418-28
• All: 5 reference(s)