Chordc1^tm1Mbra
Targeted Allele Detail

Summary

• Symbol: Chordc1^tm1Mbra
• Name: cysteine and histidine rich domain containing 1; targeted mutation 1, Mara Brancaccio
• MGI ID: MGI:4441499
• Synonyms: morgana^-
• Gene: Chordc1 Location: Chr9:18203563-18225296 bp, + strand Genetic Position: Chr9, 7.01 cM, cytoband A3
• Alliance: Chordc1^tm1Mbra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159109
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ gene and neo cassette replaced 30 nucleotides in exon 1 including the translation initiation site. (J:159109)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chordc1 Mutation: 22 strains or lines available

References

• Original: J:159109 Ferretti R, et al., Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis. Dev Cell. 2010 Mar 16;18(3):486-95
• All: 2 reference(s)