Tg(ITGAL-Ptprc)FWcr
Transgene Detail

Summary

• Symbol: Tg(ITGAL-Ptprc)FWcr
• Name: transgene insertion F, William C Raschke
• MGI ID: MGI:4442157
• Synonyms: HE
• Transgene: Tg(ITGAL-Ptprc)FWcr Location: unknown
• Alliance: Tg(ITGAL-Ptprc)FWcr page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ITGAL-Ptprc)FWcr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ptprc (MGI:97810)

• Mutation details: The human promoter was used to drive leukocyte-specific expression of the minigene. Founder line F was establish and has 15 copies of the transgene. (J:115557)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:115557 Virts EL, et al., A CD45 minigene restores regulated isoform expression and immune function in CD45-deficient mice: therapeutic implications for human CD45-null severe combined immunodeficiency. Blood. 2003 Feb 1;101(3):849-55
• All: 8 reference(s)