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Il25tm1Cdon
Targeted Allele Detail
Summary
Symbol: Il25tm1Cdon
Name: interleukin 25; targeted mutation 1, Chen Dong
MGI ID: MGI:4442364
Gene: Il25  Location: Chr14:55170152-55173294 bp, + strand  Genetic Position: Chr14, 28.0 cM
Alliance: Il25tm1Cdon page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158594
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 2 and 3 were floxed and a neo cassette inserted after exon 3 but before the second loxP site by homologous recombination. (J:158594)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il25 Mutation:  16 strains or lines available
References
Original:  J:158594 Angkasekwinai P, et al., Regulation of IL-9 expression by IL-25 signaling. Nat Immunol. 2010 Mar;11(3):250-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory