Prkra^lear
Spontaneous Allele Detail

Summary

• Symbol: Prkra^lear
• Name: protein kinase, interferon inducible double stranded RNA dependent activator; little ears
• MGI ID: MGI:4442387
• Gene: Prkra Location: Chr2:76460242-76478359 bp, - strand Genetic Position: Chr2, 45.07 cM
• Alliance: Prkra^lear page

Small ears and smaller body size of Prkra^lear/Prkra^lear female (left) compared to heterozygote (right) at nine weeks of age

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous mutation has a T-to-A transversion at chromosome 2:76,639,197 (GRCm38) in intron 5 immediately adjacent to the conserved splice donor site. (J:176116, J:222308, J:223062)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkra Mutation: 24 strains or lines available

References

• Original: J:159349 Curtain MM, et al., An Ear Pinna Mutation in the Mouse on Chromosome Two. MGI Direct Data Submission. 2010
• All: 5 reference(s)