Ugcg^tm4Rlp
Targeted Allele Detail

Summary

• Symbol: Ugcg^tm4Rlp
• Name: UDP-glucose ceramide glucosyltransferase; targeted mutation 4, Richard L Proia
• MGI ID: MGI:4442647
• Synonyms: Ugcg^loxP
• Gene: Ugcg Location: Chr4:59189452-59222833 bp, + strand Genetic Position: Chr4, 32.44 cM, cytoband B3
• Alliance: Ugcg^tm4Rlp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103415
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 7 and a floxed neo cassette was inserted into the 3'UTR downstream of exon 9. (J:103415)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ugcg Mutation: 87 strains or lines available

References

• Original: J:103415 Yamashita T, et al., Conditional LoxP-flanked glucosylceramide synthase allele controlling glycosphingolipid synthesis. Genesis. 2005 Dec;43(4):175-80
• All: 2 reference(s)