Gpr149^tm1.1Zuk
Targeted Allele Detail

Summary

• Symbol: Gpr149^tm1.1Zuk
• Name: G protein-coupled receptor 149; targeted mutation 1.1, Martin M Matzuk
• MGI ID: MGI:4442841
• Gene: Gpr149 Location: Chr3:62436851-62512861 bp, - strand Genetic Position: Chr3, 29.97 cM
• Alliance: Gpr149^tm1.1Zuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158302
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed exon 1 and the neo cassette. The absence of transcript expression was confirmed by RT-PCR on oocyte extracts. (J:158302)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr149 Mutation: 38 strains or lines available

References

• Original: J:158302 Edson MA, et al., Deletion of the novel oocyte-enriched gene, Gpr149, leads to increased fertility in mice. Endocrinology. 2010 Jan;151(1):358-68
• All: 1 reference(s)