Nlrp3^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nlrp3^m1Btlr
• Name: NLR family, pyrin domain containing 3; mutation 1, Bruce Beutler
• MGI ID: MGI:4442850
• Synonyms: ND1
• Gene: Nlrp3 Location: Chr11:59432395-59457781 bp, + strand Genetic Position: Chr11, 37.73 cM, cytoband B1.3
• Alliance: Nlrp3^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation comprises a T to G transversion at position 3187 of the mRNA, in the ninth of the gene's ten exons. It causes replacement of cysteine by tryptophan at amino acid 987 of the protein. (J:159357)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nlrp3 Mutation: 64 strains or lines available

References

• Original: J:159357 Beutler B, ND1 is an allele of Nlrp3. MGI Direct Data Submission. 2010
• All: 1 reference(s)