Slc7a11^m1Mtka
Chemically induced Allele Detail

Summary

• Symbol: Slc7a11^m1Mtka
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; mutation 1, Masato Tanaka
• MGI ID: MGI:4442905
• Synonyms: xCT^mu
• Gene: Slc7a11 Location: Chr3:50319385-50403947 bp, - strand Genetic Position: Chr3, 21.72 cM, cytoband D
• Alliance: Slc7a11^m1Mtka page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to T transversion in exon 10 that results in a premature termination at position 383 glycine. (J:159323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc7a11 Mutation: 49 strains or lines available

References

• Original: J:159323 Nabeyama A, et al., xCT deficiency accelerates chemically induced tumorigenesis. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6436-41
• All: 2 reference(s)