Camk4^tm1Tsmi
Targeted Allele Detail

Summary

• Symbol: Camk4^tm1Tsmi
• Name: calcium/calmodulin-dependent protein kinase IV; targeted mutation 1, Tsuyoshi Miyakawa
• MGI ID: MGI:4442999
• Gene: Camk4 Location: Chr18:33067984-33324281 bp, + strand Genetic Position: Chr18, 18.15 cM
• Alliance: Camk4^tm1Tsmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158693
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: The exon containing the start codon, was replaced with a neo cassette by homologous recombination. Western blotting of brain extracts demonstrated the absence of wild-type protein. (J:158693)

Generation of the Camk4^tm1Tsmi allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camk4 Mutation: 39 strains or lines available

References

• Original: J:158693 Takao K, et al., Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice. PLoS One. 2010;5(3):e9460
• All: 2 reference(s)