Sall1^{tm5(cre/ERT2)Ryn}
Targeted Allele Detail

Summary

• Symbol: Sall1^{tm5(cre/ERT2)Ryn}
• Name: spalt like transcription factor 1; targeted mutation 5, Ryuichi Nishinakamura
• MGI ID: MGI:4443031
• Synonyms: Sall1CreER^T2
• Gene: Sall1 Location: Chr8:89753867-89770790 bp, - strand Genetic Position: Chr8, 43.51 cM, cytoband D
• Alliance: Sall1^{tm5(cre/ERT2)Ryn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159446
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Sall1^{tm5(cre/ERT2)Ryn} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sall1 (MGI:1889585)

• Mutation details: The targeting vector consists of a cre/ERT2 fragment fused in-frame with a Sall1 homologous region, a neomycin-resistance gene, a 3' homologous fragment, and a diphtheria toxin A subunit selection cassette in tandem. Homologous recombination was performed in ES cells. The N-terminal amino acids of Sall1 are fused to the cre/ERT2 sequence in the recombined allele. (J:159446)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sall1 (mouse) Summary of all recombinase alleles driven by Sall1. Comparative matrix view of recombinase activities Alliance mouse Sall1 gene page

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall1 Mutation: 78 strains or lines available

References

• Original: J:159446 Inoue S, et al., A mouse line expressing Sall1-driven inducible Cre recombinase in the kidney mesenchyme. Genesis. 2010 Mar;48(3):207-12
• All: 20 reference(s)