Sall1^tm4.1Ryn
Targeted Allele Detail

Summary

• Symbol: Sall1^tm4.1Ryn
• Name: spalt like transcription factor 1; targeted mutation 4.1, Ryuichi Nishinakamura
• MGI ID: MGI:4443121
• Synonyms: Sall1^flox
• Gene: Sall1 Location: Chr8:89753867-89770790 bp, - strand Genetic Position: Chr8, 43.51 cM, cytoband D
• Alliance: Sall1^tm4.1Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159449
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upsteam of exon 1 and an additional loxP site inserted downstream of exon 1. Cre mediated recombination removed the neo cassette leaving exon 1 floxed. (J:159449)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sall1 Mutation: 78 strains or lines available

References

• Original: J:159449 Yuri S, et al., Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells. 2009 Apr;27(4):796-805
• All: 11 reference(s)