Esrp1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Esrp1^m1Btlr
• Name: epithelial splicing regulatory protein 1; mutation 1, Bruce Beutler
• MGI ID: MGI:4450974
• Synonyms: triaka
• Gene: Esrp1 Location: Chr4:11331933-11386783 bp, - strand Genetic Position: Chr4, 5.11 cM
• Alliance: Esrp1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation comprises an A to G transition at position 828 of the mRNA sequence (NM_194055 from NCBI Build 37.1), in the fourth of the gene's 16 exons. It results in replacement of methionine by valine at amino acid position 161 of the protein. (J:201716) Additional incidental mutations were detected in sequencing for the causative mutation, Esrp1^m1Btlr, and may be present in stocks carrying this mutation.
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Esrp1 Mutation: 19 strains or lines available

References

• Original: J:201716 Beutler B, Direct Data Submission 2010/05/13. MGI Direct Data Submission. 2010
• All: 3 reference(s)