C1qtnf7^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: C1qtnf7^{tm1(KOMP)Vlcg}
• Name: C1q and tumor necrosis factor related protein 7; targeted mutation 1, Velocigene
• MGI ID: MGI:4452854
• Synonyms: Ctrp7-KO
• Gene: C1qtnf7 Location: Chr5:43672881-43776145 bp, + strand Genetic Position: Chr5, 23.78 cM
• Alliance: C1qtnf7^{tm1(KOMP)Vlcg} page
• IMPC: C1qtnf7 gene page

Mutation origin

• Mutant Cell Lines: 12585C-A2, 12585C-A12, 12585C-D10, 12585C-E6
• Germline Transmission: Earliest citation of germline transmission: J:244352
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7262bp between positions 43766406-43773667 of exon 2 and most of exon 3) of Chromosome 5 (Build GRCm39). Semi-quantitative PCR confirmed the absence of transcript expression in epididymal what adipose tissue and lung. (J:136110, J:244352)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any C1qtnf7 Mutation: 22 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)