Tex19.1^tm1Hjc
Targeted Allele Detail

Summary

• Symbol: Tex19.1^tm1Hjc
• Name: testis expressed gene 19.1; targeted mutation 1, Howard J Cooke
• MGI ID: MGI:4453204
• Gene: Tex19.1 Location: Chr11:121036969-121039140 bp, + strand Genetic Position: Chr11, 85.0 cM
• Alliance: Tex19.1^tm1Hjc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159793
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a neo cassette. The absence of protein expression was confirmed by immunohistochemistry on germ cells and western blot analysis on testes extracts. (J:159793)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tex19.1 Mutation: 10 strains or lines available

References

• Original: J:159793 Ollinger R, et al., Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice. PLoS Genet. 2008;4(9):e1000199
• All: 5 reference(s)