Arg1^tm1.1Lky
Targeted Allele Detail

Summary

• Symbol: Arg1^tm1.1Lky
• Name: arginase, liver; targeted mutation 1.1, Richard M Locksley
• MGI ID: MGI:4453214
• Synonyms: Arg1^Yarg, Arg1^YFP, YARG
• Gene: Arg1 Location: Chr10:24791105-24803368 bp, - strand Genetic Position: Chr10, 12.26 cM
• Alliance: Arg1^tm1.1Lky page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122735
• Parent Cell Line: PC3 (ES Cell)
• Strain of Origin: 129S4/SvJae-Tg(Prm-cre)70Og

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES element linked to an enhanced YFP construct was inserted in exon 8 downstream of the endogenous stop codon and a floxed neomycin cassette. The neomycin selection cassette was excised in male mice by cre expressed from the Prm1 promoter. (J:122735)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Arg1 Mutation: 28 strains or lines available

References

• Original: J:122735 Reese TA, et al., Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. 2007 May 3;447(7140):92-6
• All: 30 reference(s)