Ltbr^tm1Avt
Targeted Allele Detail

Summary

• Symbol: Ltbr^tm1Avt
• Name: lymphotoxin B receptor; targeted mutation 1, Alexei V Tumanov
• MGI ID: MGI:4453317
• Gene: Ltbr Location: Chr6:125283534-125290848 bp, - strand Genetic Position: Chr6, 59.32 cM
• Alliance: Ltbr^tm1Avt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158663
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted 5' of exon 1 and a third loxP site was inserted within intron 2 via homologous recombination. (J:158663)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ltbr Mutation: 47 strains or lines available

References

• Original: J:158663 Wang Y, et al., Lymphotoxin beta receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection. Immunity. 2010 Mar 26;32(3):403-13
• All: 17 reference(s)