Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar
Transgene Detail

Summary

• Symbol: Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar
• Name: transgene insertion, Leif Carlsson
• MGI ID: MGI:4453330
• Synonyms: Z/Lhx2-GFP
• Transgene: Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar Location: unknown
• Alliance: Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar page

Transgene origin

• Strain of Origin: C57BL/6 x 129/Sv

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lhx2 (MGI:96785)

• Mutation details: The transgene contains the CMV enhancer/chicken beta-actin promoter, a floxed beta-geo reporter/SV40 polyadenylation signal segment, and murine Lhx2 cDNA, an internal ribosomal entry site (IRES) and green fluorescent protein (GFP) followed by a rabbit Hbb polyadenylation sequence. The cells with the highest lacZ expression and a single integration were selected for blastocyst injection. (J:159209)

Generation of the Tg(CAG-Bgeo/Lhx2,-GFP)#Lcar transgene

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:159209 Tornqvist G, et al., Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904
• All: 2 reference(s)