Dnajc10^tm1Tiw
Targeted Allele Detail

Summary

• Symbol: Dnajc10^tm1Tiw
• Name: DnaJ heat shock protein family (Hsp40) member C10; targeted mutation 1, Takao Iwawaki
• MGI ID: MGI:4453462
• Synonyms: ERdj5^-
• Gene: Dnajc10 Location: Chr2:80145810-80184387 bp, + strand Genetic Position: Chr2, 48.05 cM, cytoband D
• Alliance: Dnajc10^tm1Tiw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159968
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on liver, kidney, pancreas, and spleen extracts. (J:159968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dnajc10 Mutation: 44 strains or lines available

References

• Original: J:159968 Hosoda A, et al., Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland. Biochem J. 2010 Jan 1;425(1):117-25
• All: 5 reference(s)