Trip10^tm1Sejc
Targeted Allele Detail

Summary

• Symbol: Trip10^tm1Sejc
• Name: thyroid hormone receptor interactor 10; targeted mutation 1, Seth J Corey
• MGI ID: MGI:4453577
• Synonyms: Cip4^-
• Gene: Trip10 Location: Chr17:57556455-57570665 bp, + strand Genetic Position: Chr17, 29.74 cM
• Alliance: Trip10^tm1Sejc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159952
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: Exons 1 through 3 were replaced with a lacZ gene, SV40 polyadenylation sequence, and neo cassette.The absence of protein expression was confirmed by western blot analysis on spleen, intestinal epithelium, smooth muscle, skeletal muscle, and heart extracts. (J:159952)

Generation of the Trip10^tm1Sejc allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trip10 Mutation: 31 strains or lines available

References

• Original: J:159952 Feng Y, et al., The Cdc42-interacting protein-4 (CIP4) gene knock-out mouse reveals delayed and decreased endocytosis. J Biol Chem. 2010 Feb 12;285(7):4348-54
• All: 3 reference(s)