Tg(Fabp4-LMNA)#Cdl
Transgene Detail

Summary

• Symbol: Tg(Fabp4-LMNA)#Cdl
• Name: transgene insertion, Constantine D Londos
• MGI ID: MGI:4453883
• Synonyms: LMNA-WT
• Transgene: Tg(Fabp4-LMNA)#Cdl Location: unknown
• Alliance: Tg(Fabp4-LMNA)#Cdl page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-LMNA)#Cdl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LMNA (4000)

  Lmna	(MGI:96794)

• Mutation details: The 11 kb transgenic construct contained a fatty acid binding protein (aP2) promoter to drive adipose-specific expression of the human lamin A cDNA followed by an SV40 splice site and poly(A) sites. No line number was given (denoted by #). (J:149858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:149858 Wojtanik KM, et al., The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation. J Lipid Res. 2009 Jun;50(6):1068-79
• All: 1 reference(s)