Tg(Agt)123Uhg
Transgene Detail

Summary

• Symbol: Tg(Agt)123Uhg
• Name: transgene insertion 123, University of Heidelberg
• MGI ID: MGI:4453970
• Synonyms: TGM(rAOGEN)123
• Transgene: Tg(Agt)123Uhg Location: unknown
• Alliance: Tg(Agt)123Uhg page

Transgene origin

• Strain of Origin: NMRI

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Agt)123Uhg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Agt (24179)

  Agt	(MGI:87963)

• Mutation details: The transgene contains a 14.2 kb fragment from the 14.5 kb genomic rat AOGEN clone. Three lines were created (lines 92, 102, and 123) with line 123 exhibiting a 4-fold increase in plasma angiotensinogen and ANGII levels. (J:160282)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:160282 Kimura S, et al., High blood pressure in transgenic mice carrying the rat angiotensinogen gene. EMBO J. 1992 Mar;11(3):821-7
• All: 2 reference(s)