Sall4^tm4Ryn
Targeted Allele Detail

Summary

• Symbol: Sall4^tm4Ryn
• Name: spalt like transcription factor 4; targeted mutation 4, Ryuichi Nishinakamura
• MGI ID: MGI:4454458
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^tm4Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159449
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2 and 3 were replaced with an IRES and hygro cassette. (J:118119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 145 strains or lines available

References

• Original: J:159449 Yuri S, et al., Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells. 2009 Apr;27(4):796-805
• All: 2 reference(s)