Tg(Nodal*-cre)#Mku
Transgene Detail

Summary

• Symbol: Tg(Nodal*-cre)#Mku
• Name: transgene insertion, Michael R Kuehn
• MGI ID: MGI:4454667
• Synonyms: Nodal PNC-Cre
• Transgene: Tg(Nodal*-cre)#Mku Location: unknown
• Alliance: Tg(Nodal*-cre)#Mku page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Nodal*-cre)#Mku expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Nodal

• Mutation details: A 2.8 kb genomic fragment containing the Nodal posterior notochord enhancer (PNC) was assembled with a sequence composed of the Hspa1 promoter fragment and the synthetic intron-cre-polyA cassette to create the final construct. Transgenic founders were generated and crossed to R26 reporter to identify germline transmission. No line numbers were specified. (J:130464)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nodal (species not specified) Summary of all recombinase alleles driven by Nodal. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:130464 Kumar A, et al., Transgenic mouse lines expressing Cre recombinase specifically in posterior notochord and notochord. Genesis. 2007 Dec;45(12):729-36
• All: 1 reference(s)