Tmem204^tm1.1Ali
Targeted Allele Detail

Summary

• Symbol: Tmem204^tm1.1Ali
• Name: transmembrane protein 204; targeted mutation 1.1, Kari Alitalo
• MGI ID: MGI:4454669
• Gene: Tmem204 Location: Chr17:25276676-25300088 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Tmem204^tm1.1Ali page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159519
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted 5' to exon 1 and an FRT flanked neomycin cassette followed by a loxP site was inserted within intron 1. Exon 1 has been removed by cre-mediated recombination. Absence of transcript was confirmed by RT-PCR. (J:159519)

Expression

In Mice Carrying this Mutation:	70 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem204 Mutation: 14 strains or lines available

References

• Original: J:159519 Saharinen P, et al., Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80
• All: 1 reference(s)