Tg(H2-K^b-IL21)5Wjl
Transgene Detail

Summary

• Symbol: Tg(H2-K^b-IL21)5Wjl
• Name: transgene insertion 5, Warren J Leonard
• MGI ID: MGI:4454683
• Synonyms: IL-21 TG
• Transgene: Tg(H2-K^b-IL21)5Wjl Location: unknown
• Alliance: Tg(H2-K^b-IL21)5Wjl page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K^b-IL21)5Wjl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL21 (59067)

  Il21	(MGI:1890474)

• Mutation details: The mouse H-2k^b promoter and IgM enhancer drives expression of the human cDNA with V5 and His tags. Two lines were created (line 5 and 7). (J:93740)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:93740 Ozaki K, et al., Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J Immunol. 2004 Nov 1;173(9):5361-71
• All: 1 reference(s)