Tg(KRT14-Il7)1Tsk
Transgene Detail

Summary

• Symbol: Tg(KRT14-Il7)1Tsk
• Name: transgene insertion 1, Thomas S Kupper
• MGI ID: MGI:4454778
• Synonyms: Tg(KRT14-Il7a)1Tsk
• Transgene: Tg(KRT14-Il7)1Tsk Location: unknown
• Alliance: Tg(KRT14-Il7)1Tsk page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Il7)1Tsk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il7 (MGI:96561)

• Mutation details: This transgene consists of a human keratin 14 promotor fragment driving keratinocyte-specific expression of mouse IL7 cDNA. Founder line 1 was generated. (J:42565)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:42565 Williams IR, et al., IL-7 overexpression in transgenic mouse keratinocytes causes a lymphoproliferative skin disease dominated by intermediate TCR cells: evidence for a hierarchy in IL-7 responsiveness among cutaneous T cells. J Immunol. 1997 Sep 15;159(6):3044-56
• All: 3 reference(s)