Atoh1^tm1(cre)Gan
Targeted Allele Detail

Summary

• Symbol: Atoh1^tm1(cre)Gan
• Name: atonal bHLH transcription factor 1; targeted mutation 1, Lin Gan
• MGI ID: MGI:4455013
• Synonyms: Atoh1^cre
• Gene: Atoh1 Location: Chr6:64706109-64708229 bp, + strand Genetic Position: Chr6, 30.03 cM
• Alliance: Atoh1^tm1(cre)Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160667
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Atoh1^tm1(cre)Gan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atoh1 (MGI:104654)

• Mutation details: A targeting construct was used to replace the complete coding sequence of Atoh1 with the cre recombinase sequence so that cre expression was controlled by the Atoh1 regulatory sequences. The knockin allele was generated in W4 ES cells. (J:160667)

Generation of the Atoh1^tm1(cre)Gan allele

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Comparative matrix view of recombinase activities Alliance mouse Atoh1 gene page

Expression

In Mice Carrying this Mutation:

20 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh1 Mutation: 37 strains or lines available

References

• Original: J:160667 Yang H, et al., Generation and characterization of Atoh1-Cre knock-in mouse line. Genesis. 2010 Apr 13;48(6):407-413
• All: 39 reference(s)