Prss12tm1Mits
Targeted Allele Detail
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| Symbol: |
Prss12tm1Mits |
| Name: |
serine protease 12 neurotrypsin (motopsin); targeted mutation 1, Shinichi Mitsui |
| MGI ID: |
MGI:4456117 |
| Synonyms: |
motopsin KO |
| Gene: |
Prss12 Location: Chr3:123240562-123300246 bp, + strand Genetic Position: Chr3, 54.58 cM, cytoband G3
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| Alliance: |
Prss12tm1Mits page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:157626
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A PGKneo cassette replaced exon 1 of the gene by homologous recombination. The lack of protein was confirmed by immunohistochemistry on brain tissue.
(J:157626)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Prss12 Mutation: |
37 strains or lines available
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| Original: |
J:157626 Mitsui S, et al., A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction. Eur J Neurosci. 2009 Dec;30(12):2368-78 |
| All: |
2 reference(s) |
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Analysis Tools
