Tg(AMH-Fshr*D580Y)#Hht
Transgene Detail

Summary

• Symbol: Tg(AMH-Fshr*D580Y)#Hht
• Name: transgene insertion, Ilpo Huhtaniemi
• MGI ID: MGI:4456201
• Synonyms: mFshr^D580Y, Tg(AMH-FSHR^D580Y)
• Transgene: Tg(AMH-Fshr*D580Y)#Hht Location: unknown
• Alliance: Tg(AMH-Fshr*D580Y)#Hht page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(AMH-Fshr*D580Y)#Hht expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fshr (MGI:95583)	Transgene codes for protein with aspartic acid to tyrosine mutation.

• Mutation details: The transgene contains a 3.6 kb human AMH promoter, and a murine Fshr with Asp580Tyr mutation. Line number 5 and 11 were used in the study. (J:160015)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:160015 Peltoketo H, et al., Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess. Endocrinology. 2010 Apr;151(4):1872-83
• All: 1 reference(s)