Gmnn^tm1.2Kio
Targeted Allele Detail

Summary

• Symbol: Gmnn^tm1.2Kio
• Name: geminin; targeted mutation 1.2, Dimitris Kioussis
• MGI ID: MGI:4456373
• Gene: Gmnn Location: Chr13:24935828-24945906 bp, - strand Genetic Position: Chr13, 10.64 cM
• Alliance: Gmnn^tm1.2Kio page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159657
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed the neo cassette, exon 3 and exon 4. The absence of protein expression was confirmed by western blot analysis on thymus and spleen extracts. (J:159657)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gmnn Mutation: 27 strains or lines available

References

• Original: J:159657 Karamitros D, et al., Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 2010 Mar 1;184(5):2432-41
• All: 2 reference(s)